Lisa has had a long-standing interest in host-pathogen interactions and how the regulation of inflammation and immunity intersect. After completing her PhD (Ninan Abraham, UBC 2010), she pursued post-doctoral research with David Artis at the University of Pennsylvania where she received fellowship support from the Cancer Research Institute as an Edmond J Safra scholar. In 2015, she joined the Microbiology & Immunology department at UBC as the Canada Research Chair in Host-Microbiome Interactions.
JUNG HEE SEO
PhD Lab Manager
Jung Hee has been at UBC for over 10 years, and in the Osborne Lab since 2015. Her extensive molecular biology, tissue culture and managerial skills keep the whole place running smoothly.
PhD Candidate (09/2016 - )
The exact cause of the autoimmune neurodegenerative disease - Multiple Sclerosis - remains unknown, however susceptibility has been linked to environmental factors. Hannah is studying the impact of diet on multiple sclerosis and testing helminth excretory products as potential therapeutics for inflammatory diseases.
PhD Candidate (01/2017 - )
The intestinal epithelium is the site of truly staggering amounts of interspecies interactions. Using fluorescent microscopy in tandem with other techniques Blair’s project is attempting to characterize the underlying cellular conversations among different immune cells and the epithelial cells that make up the bulk of the intestinal tissue involved in preventing infection while also maintaining intestinal homeostasis.
When not in the lab Blair plays hockey, gardens, and spends as much time as possible wandering the coast and coastal rivers fly-fishing.
PhD Candidate (09/2017 - )
Our guts are inhabited by countless viruses, but little is known about how our immune system controls these infections, or how they influence our immunity to unrelated pathogens. Andrew is studying how the immune signaling molecule STAT1 coordinates our immune response to these viruses by exploring the consequences of STAT1-deficiency. In tandem, Andrew is investigating how common pharmaceuticals can shape our immune responses to intestinal viruses
Outside of the lab, Andrew leads science outreach programs for children and adults, and skis as much as possible.
PhD Candidate (09/2018 - )
Multiple sclerosis (MS) is a debilitating chronic neurodegenerative disease that affects nearly 100 000 Canadians. The exact cause of MS remains unknown, although there is mounting evidence to suggest that environmental factors, including infection with Epstein-Barr virus and dysregulation of the gut microbiome, play important roles in disease progression. Naomi’s project explores the intersecting roles of these environmental factors and how they may interact with the host and each other to influence initiation and progression of MS.
Honor’s Student (01/2018 - )
Navid began as a volunteer student in January of 2018 and is now eager to pursue a directed studies project with the mentorship of both Lisa and Blair. He is in his final year of the UBC Microbiology and Immunology Honours program. In the lab, Navid is interested in intestinal in-vitro models for testing the effects of helminth and viral infections.
Honor’s Student (09/2018 - )
Sarah's project focuses primarily on characterizing the immune cell responsible for initiating the adaptive response against specific viral infections in the gut using in vivo modelling and flow cytometry.
Heather Filyk, Msc
Wallace Yuen, BSc